Immune Biomarkers Predictive of Respiratory Viral Infection in Elderly Nursing Home Residents

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Immune Biomarkers Predictive of Respiratory Viral Infection in Elderly Nursing Home Residents

OBJECTIVE To determine if immune phenotypes associated with immunosenescence predict risk of respiratory viral infection in elderly nursing home residents. METHODS Residents ≥ 65 years from 32 nursing homes in 4 Canadian cities were enrolled in Fall 2009, 2010 and 2011, and followed for one influenza season. Following influenza vaccination, peripheral blood mononuclear cells (PBMCs) were obta...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2014

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0108481